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Article

Targets of influenza human T-cell response are mostly conserved in H5N1

23 Dec 2024

Abstract excerpt

Frequent recent spillovers of subtype H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI) virus into poultry and mammals, especially dairy cattle, including several human cases, increased concerns over a possible future pandemic. Here, we performed an analysis of epitope data curated in the Immune Epitope Database (IEDB). We found that the patterns of immunodominance of seasonal influenza viruses...

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PMID: 39714185
DOI: 10.1128/mbio.03479-24

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