Article

Emerging SARS-CoV-2 variants reduce neutralization sensitivity to convalescent sera and monoclonal antibodies

2021-01-22

Abstract excerpt

<h4>ABSTRACT</h4> SARS-CoV-2 Spike-specific antibodies contribute the majority of the neutralizing activity in most convalescent human sera. Two SARS-CoV-2 variants, N501Y.V1 (also known as B.1.1.7 lineage or VOC-202012/01) and N501Y.V2 (B.1.351 lineage), reported from the United Kingdom and South Africa, contain several mutations in the receptor binding domain of Spike and are of particular concern. To address t...

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Literature Corpus work: fb8a1856-a69c-502b-ae6c-68df45553347
DOI: 10.1101/2021.01.22.427749

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