Article
Simplified fecal community transplant restores <i>Clostridioides difficile</i> colonization resistance to antibiotic perturbed murine communities
2022-05-12
Abstract excerpt
Fecal communities transplanted into individuals can eliminate recurrent Clostridioides difficile infection (CDI) with high efficacy. However, this treatment is only used once CDI becomes resistant to antibiotics or has recurred multiple times. We sought to investigate whether a fecal community transplant (FCT) pre-treatment could be used to prevent CDI altogether. We treated male C57BL/6 mice with either clindamy...
Topics
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- Bacterial Identification and Susceptibility Testing
- Clostridium difficile and Clostridium perfringens research
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Microscopic Colitis
- Pharmacological Effects of Natural Compounds
- Probiotics and Fermented Foods
- Salmonella and Campylobacter epidemiology
Identifiers and source
- Literature Corpus work
- 4e6c8126-431a-53d7-afee-89517b9f6379
- DOI
- 10.1101/2022.05.11.491589
