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Host origin of microbiota drives functional recovery and <i>Clostridioides difficile</i> clearance in mice

2024-11-19

Abstract excerpt

Colonization resistance provided by the gut microbiota is essential for resisting both initial Clostridioides difficile infection (CDI) and potential recurrent infection (rCDI). Although fecal microbiota transplantation (FMT) has been successful in treating rCDI by restoring microbial composition and function, mechanisms underlying efficacy of standardized stool-derived products remain poorly understood. Using a...

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Literature Corpus work
088a6f4d-e7f0-5ac6-83fc-c44d334afd98
DOI
10.1101/2024.11.19.624317
Open publication

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Host origin of microbiota drives functional recovery and <i>Clostridioides difficile</i> clearance in miceDOI 10.1101/2024.11.19.624317
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