Article
CFTR dysfunction in cystic fibrosis and chronic obstructive pulmonary disease.
Expert review of respiratory medicine - 1 Jun 2018
Fernandez Fernandez Elena, De Santi Chiara, De Rose Virginia, Greene Catherine M
Abstract excerpt
INTRODUCTION: Obstructive lung diseases such as cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are causes of high morbidity and mortality worldwide. CF is a multiorgan genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene and is characterized by progressive chronic obstructive lung disease. Most cases of COPD are a result of noxious...
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