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Article

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

2026-01-05

Abstract excerpt

<h4>Background: </h4> The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder (BD) remains limited. <h4>Aim:</h4> To enhance prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes implicated in lithium response and/or BD aetiology. <h4>Methods:</h4> We analysed data collected from BD patients wh...

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Literature Corpus work
4e594ad8-3d3b-51a5-ae8e-7d58557dd7d7
DOI
10.64898/2026.01.01.25343187
Open publication

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