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Pathway-Specific Polygenic Scores for Lithium Response for Predicting Clinical Lithium Treatment Response in Patients with Bipolar Disorder

2025-03-24

Abstract excerpt

<h4>Background</h4> Polygenic scores (PGSs) hold the potential to identify patients who respond favourably to specific psychiatric treatments. However, their biological interpretations remain unclear. In this study, we developed pathway-specific PGSs (PS PGS ) for lithium response and assessed their association with clinical lithium response in patients with bipolar disorder (BD). <h4>Methods</h4> Using sets of ge...

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Literature Corpus work
edf4d94e-0c8e-5623-abda-0361206904d6
DOI
10.1101/2025.03.20.25324216
Open publication

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Pathway-Specific Polygenic Scores for Lithium Response for Predicting Clinical Lithium Treatment Response in Patients with Bipolar DisorderDOI 10.1101/2025.03.20.25324216
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