Article

Modeling gene x environment interactions in PTSD using glucocorticoid-induced transcriptomics in human neurons

2021-03-02

Abstract excerpt

<h4>ABSTRACT</h4> Post-traumatic stress disorder (PTSD) results from severe trauma exposure, but the extent to which genetic and epigenetic risk factors impact individual clinical outcomes is unknown. We assessed the impact of genomic differences following glucocorticoid administration by examining the transcriptional profile of human induced pluripotent stem cell (hiPSC)-derived glutamatergic neurons and live cu...

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Literature Corpus work: 4e44cae6-b607-598b-b0c5-4373cf44189c
DOI: 10.1101/2021.03.01.433391

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