Article
Post-biopsy cell-free DNA from blood: an open window on primary prostate cancer genetics and biology
2021-01-19
Abstract excerpt
<title>Abstract</title> <p>BackgroundCirculating cell-free DNA (ccfDNA), released from normal and cancerous cells, is a promising biomarker for cancer detection as in neoplastic patients it is enriched in tumor-derived DNA (ctDNA). ctDNA contains cancer-specific mutations and epigenetic modifications, which can have diagnostic/prognostic value. However, in primary tumors, and in particular in localized prostate c...
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Identifiers and source
- Literature Corpus work
- 4e37dd6c-e779-540c-af33-7466cb8db94e
- DOI
- 10.21203/rs.3.rs-147849/v1
