Article
Liquid biopsy with cell free DNA: new horizons for prostate cancer.
Critical reviews in clinical laboratory sciences - 1 Jan 2021
Ponti Giovanni, Maccaferri Monia, Percesepe Antonio, Tomasi Aldo, Ozben Tomris
Abstract excerpt
Although prostate cancer (PCa) is one of the most common tumors in European males, the only minimally invasive diagnostic tool in PCa setup is the determination of PSA in serum. Cell-free DNA (cfDNA) has been demonstrated to be helpful for PCa diagnosis but has not yet been integrated into the clinical setting. This review aims to provide a systematic update of cfDNA and its fragmentation patterns in PCa reported...
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