Article

Alterations of Chromatin Accessibility of Human Mesenchymal Stem Cells During Early Differentiation Stage Toward Osteoblasts and Adipocyte

2021-11-12

Abstract excerpt

Although differential expression of genes is apparent during the adipogenic/osteogenic differentiation of marrow mesenchymal stem cells (MSCs), it is not known whether this is associated with changes in chromosomal structure. In this study, we used ATAC-sequencing technology to observe variations in chromatin assembly during the early stages of MSC differentiation. This showed significant changes in the number and...

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Literature Corpus work: 4e35b779-298f-5983-9a5b-4e4cc85b9877
DOI: 10.21203/rs.3.rs-1055172/v1

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