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Chromatin accessibility identifies diversity in mesenchymal stem cells from different tissue origins

4 Dec 2018

Abstract excerpt

Mesenchymal stem cells (MSCs), which can differentiate into tri-lineage (osteoblast, adipocyte, and chondrocyte) and suppress inflammation, are promising tools for regenerative medicine. MSCs are phenotypically diverse based on their tissue origins. However, the mechanisms underlying cell-type-specific gene expression patterns are not fully understood due to the lack of suitable strategy to identify the...

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PMID: 30531792
DOI: 10.1038/s41598-018-36057-0

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