Article
Epigenetic regulation of human adipose-derived stem cells differentiation.
Molecular and cellular biochemistry - 1 Dec 2015
Daniunaite Kristina, Serenaite Inga, Misgirdaite Roberta, Gordevicius Juozas, Unguryte Ausra, Fleury-Cappellesso Sandrine, Bernotiene Eiva, Jarmalaite Sonata
Abstract excerpt
Adult stem cells have more restricted differentiation potential than embryonic stem cells (ESCs), but upon appropriate stimulation can differentiate into cells of different germ layers. Epigenetic factors, including DNA modifications, take a significant part in regulation of pluripotency and differentiation of ESCs. Less is known about the epigenetic regulation of these processes in adult stem cells. Gene...
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