Article

Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: A theranostic study for the precision medicine

2020-09-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Lung squamous cell carcinoma (LSCC) remains a challenging disease to treat, and further improvements in prognosis are dependent upon the identification of LSCC-specific therapeutic biomarkers and/or targets. We previously found that Syntaxin Binding Protein 4 (STXBP4) plays a crucial role in lesion growth and, therefore, clinical outcomes in LSCC patients throug...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4e33bf84-1879-5a38-bdcd-cdb56d373f25
DOI: 10.21203/rs.3.rs-39783/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: A theranostic study for the precision medicineDOI 10.21203/rs.3.rs-39783/v2Read

PLEK2 and SCN7A: novel biomarkers of non-small cell lung cancerSemantic proximity Read

The RNA-binding protein La/SSB drives head and neck squamous cell carcinoma progression through TFAP2C-mediated transcriptional activation of FSCN1Semantic proximity Read

BCAP29/31 as a Poor Prognostic Biomarker for Head and Neck Squamous Carcinoma: Impacting the TGFβ1/Smad- EMT PathwaySemantic proximity Read

SYT2/11/13/15 Are Potential Prognostic Biomarkers and Correlate to Immune Infiltration in Lung AdenocarcinomaSemantic proximity Read

The γ-secretase catalytic subunit PSEN1, regulated by YY1, promotes lung adenocarcinoma progression via the Notch1/EGFR pathwaySemantic proximity Read

Abnormal genome-wide DNA methylation induced by cisplatin may contribute to the chemo-resistance of human small cell lung cancerSemantic proximity Read

FBXO28 promotes the malignancy of non-small cell lung cancer through ubiquitination-mediated activation of BRD4Semantic proximity Read

Tetraspanin CD63 reduces the progression and metastasis of head and neck squamous cell carcinoma via KRT1-mediated cell cycle arrestSemantic proximity Read

WITHDRAWN: The SOX4–PTBP2 Axis Promotes Proliferation, Invasion and Lymphatic Metastasis in Laryngeal Squamous Cell CarcinomaSemantic proximity Read

Promotion of stem cell-like phenotype of lung adenocarcinoma by FAM83A via stabilization of ErbB2.Semantic proximity Read

SPP1 promotes brain metastasis of NSCLC by up-regulating PI3K/AKT/mTOR pathwaySemantic proximity Read