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Article

Promotion of stem cell-like phenotype of lung adenocarcinoma by FAM83A via stabilization of ErbB2.

Cell death & disease - 28 Jun 2024

Yuan Ye, Hao Liang, Huang Jing-Shan, Zhao Fu-Ying, Ju Ying-Hua, Wang Jia-Mei, Zhang Ting, Li Bai-Qiang, Yu Zhan-Wu

Abstract excerpt

Lung cancer stands as the leading cause of mortality among all types of tumors, with over 40% of cases being lung adenocarcinoma (LUAD). Family with sequence similarity 83 member A (FAM83A) emerges as a notable focus due to its frequent overexpression in LUAD. Despite this, the precise role of FAM83A remains elusive. This study addresses this gap by unveiling the crucial involvement of FAM83A in maintaining the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38942760
DOI: 10.1038/s41419-024-06853-w
PMCID: PMC11213963

Genes

STUB1
STIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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