Article

FBXO28 promotes the malignancy of non-small cell lung cancer through ubiquitination-mediated activation of BRD4

2024-04-19

Abstract excerpt

<title>Abstract</title> <p>The E3 ubiquitin ligase FBXO28 has been implicated in the progression of various cancers, yet its precise function and substrates remain poorly understood. In this study, we investigated the role of FBXO28 in non-small cell lung cancer (NSCLC) and its impact on patient prognosis. We observed an upregulation of FBXO28 in NSCLC, and higher FBXO28 levels correlated with poorer patient outc...

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Literature Corpus work: d148f0ed-7e05-5a27-b1c8-2de190bd46f2
DOI: 10.21203/rs.3.rs-3615557/v1

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