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SPP1 promotes brain metastasis of NSCLC by up-regulating PI3K/AKT/mTOR pathway

2023-10-31

Abstract excerpt

<h4>Purpose: </h4> Brain metastasis (BM) is a significant contributor to poor prognosis in patients with non-small cell lung cancer (NSCLC). Secreted phosphoprotein 1 (SPP1) is involved in the progression and metastasis of various cancers. However, the role of SPP1 in NSCLC, particularly in NSCLC BM, remains unclear. This study aimed to identify genes associated with NSCLC BM and investigate the involvement of SPP...

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Literature Corpus work
6da283ad-960c-5b6e-bfcc-aa25fef8a673
DOI
10.21203/rs.3.rs-3499680/v1
Open publication

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SPP1 promotes brain metastasis of NSCLC by up-regulating PI3K/AKT/mTOR pathwayDOI 10.21203/rs.3.rs-3499680/v1
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