Article

Phosphorylation of the M1 muscarinic acetylcholine receptor mediates protection in neurodegenerative disease

2021-04-29

Abstract excerpt

There are currently no treatments that can slow the progression of neurodegenerative diseases such as Alzheimer’s disease (AD). There is, however, a growing body of evidence that activation of the M1 muscarinic acetylcholine receptor (M1-receptor) can not only restore memory loss in AD patients, but in preclinical animal models can also slow neurodegenerative disease progression. The generation of an effective med...

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Literature Corpus work: 4e1e5500-88c7-5be2-9808-ec600ef37817
DOI: 10.1101/2021.04.29.440753

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