Article

Improved Quality Metrics for Association and Reproducibility in Chromatin Accessibility Data Using Mutual Information

2023-04-29

Abstract excerpt

<h4>Background</h4> Correlation metrics are widely utilized in genomics analysis and often implemented with little regard to assumptions of normality, homoscedasticity, and independence of values. This is especially true when comparing values between replicated sequencing experiments that probe chromatin accessibility, such as assays for transposase-accessible chromatin via sequencing (ATAC-seq). Such data can po...

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Literature Corpus work: 4dd109da-d7c5-5f92-ac92-a516145f1d19
DOI: 10.1101/2023.04.26.538354

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