Statistical Association Mapping of Population-Structured Genetic Data

Abstract excerpt

Association mapping of genetic diseases has attracted extensive research interest during the recent years. However, most of the methodologies introduced so far suffer from spurious inference of the disease-causing sites due to population inhomogeneities. In this paper, we introduce a statistical framework to compensate for this shortcoming by equipping the current methodologies with a state-of-the-art clustering a...

Topics

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• Algorithms
• Asian People
• Cluster Analysis
• Genetics, Population
• Genome, Human
• Human Genome Project
• Models, Theoretical
• Sample Size

Identifiers and source

Literature Corpus work

4dcb8825-f69f-5870-8a16-8876a7e635ec

DOI

10.1101/069658