Article
A Bayesian hierarchical model for allele frequencies.
Genetic epidemiology - 1 Jan 2001
Lockwood J R, Roeder K, Devlin B
Abstract excerpt
Genetic epidemiological methodologies, such as linkage analysis, often require accurate estimates of allele frequencies. When studies involve multiple sub-populations with different evolutionary histories, accurate estimates can be difficult to obtain because the number of subjects per sub-population tends to be limited. Given allele counts for a collection of loci and sub-populations, we propose a Bayesian...
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