Article

A delta-tubulin/epsilon-tubulin/Ted protein complex is required for centriole architecture

2024-04-20

Abstract excerpt

Centrioles have a unique, conserved architecture formed by three linked “triplet” microtubules arranged in nine-fold symmetry. The mechanisms by which these triplet microtubules are formed are not understood and likely involve the noncanonical tubulins delta-tubulin and epsilon-tubulin. Previously, we found that human cells deficient in delta-tubulin or epsilon-tubulin form abnormal centrioles, characterized by an...

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Literature Corpus work: 4db217d3-63de-5c9c-8584-c27e50de21f8
DOI: 10.1101/2024.04.19.590208

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