Back to search

Article

The Human Proteoform Project: A Plan to Define the Human Proteome

2020-10-19

Abstract excerpt

Proteins are the primary effectors of function in biology, and thus complete knowledge of their structure and properties is fundamental to deciphering function in basic and translational research. The chemical diversity of proteins is expressed in their many proteoforms, which result from combinations of genetic polymorphisms, RNA splice variants and post-translational modifications. This knowledge is foundational...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4d9ae877-ab53-5be7-9891-7e62d9f23f89
DOI
10.20944/preprints202010.0368.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Human Proteoform Project: A Plan to Define the Human ProteomeDOI 10.20944/preprints202010.0368.v1
The Human Proteoform Atlas: a FAIR community resource for experimentally derived proteoforms.Semantic proximity
Proteogenomics: Integrating Next-Generation Sequencing and Mass Spectrometry to Characterize Human Proteomic Variation.Semantic proximity
How many human proteoforms are there?Semantic proximity
N-Terminal Proteoforms in Human DiseaseSemantic proximity
Proteogenomics: Key Driver for Clinical Discovery and Personalized Medicine.Semantic proximity
The human proteome size as a technological development function.Semantic proximity
The Blood Proteoform Atlas: A reference map of proteoforms in human hematopoietic cellsSemantic proximity
2DE-pattern: A Database for Inventory of Human ProteoformsSemantic proximity
Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome ProjectSemantic proximity
Metrics for the Human Proteome Project 2016: Progress on Identifying and Characterizing the Human Proteome, Including Post-Translational Modifications.Semantic proximity
A Database “2DE-Pattern” for Inventory of Proteoform Profiles: 2026 Upgrade and Update on OutcomesSemantic proximity
Proteoforms as the next proteomics currency.Semantic proximity
Select a neighboring publication to make it the new centre.