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Article

The human proteome size as a technological development function.

Biomeditsinskaia khimiia - 1 Sept 2024

Sarygina E V, Kozlova A S, Ponomarenko E A, Ilgisonis E V

Abstract excerpt

Changes in information on the number of human proteoforms, post-translational modification (PTM) events, alternative splicing (AS), single-amino acid polymorphisms (SAP) associated with protein-coding genes in the neXtProt database have been retrospectively analyzed. In 2016, our group proposed three mathematical models for predicting the number of different proteins (proteoforms) in the human proteome. Eight...

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PMID: 39324201
DOI: 10.18097/PBMC20247005364

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