Article

Identification of potential biomarker candidates of drug-induced vascular injury (DIVI) in rats using gene expression and histopathology data

2022-08-27

Abstract excerpt

Drug-induced vascular injury (DIVI) observed in non-clinical species often leads to significant delays or termination of compounds in drug development due to the lack of translatable biomarkers and unknown relevance to humans. This study focused on the identification of potential biomarker candidates of drug-induced vascular injury, or more specifically mesenteric medial arterial necrosis (MAN), in rats. To do so,...

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Literature Corpus work: 4d71951a-1e7d-591d-bd44-87af0ad783eb
DOI: 10.1101/2022.08.24.505120

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Identification of potential biomarker candidates of drug-induced vascular injury (DIVI) in rats using gene expression and histopathology dataDOI 10.1101/2022.08.24.505120Read

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