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Revealing the Underlying Mechanism of Ischemia Reperfusion Injury Using Bioinformatics Approach

1 Jan 2013

Abstract excerpt

BACKGROUND/AIMS: To reveal the potential pathogenesis of ischemia/reperfusion (I/R) injury. METHODS: GSE9943 were downloaded from Genome Expression Omnibus database, including I/R and control samples for both Brown Norway (BN) and Sprague Dawley (SD) rats (3 rats/each group). Then differentially expressed genes (DEGs) were identified by limma package. miRNA-target gene network pairs were predicted using...

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PMID: 24603189
DOI: 10.1159/000355759

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