Article
Effects of lycopene on the insulin-like growth factor (IGF) system in premenopausal breast cancer survivors and women at high familial breast cancer risk.
Nutrition and cancer - 1 Jan 2008
Voskuil Dorien W, Vrieling Alina, Korse Catharina M, Beijnen Jos H, Bonfrer Johannes M G, van Doorn Jaap, Kaas Reinie, Oldenburg Hester S A, Russell Nicola S, Rutgers Emiel J T, Verhoef Senno, van Leeuwen Flora E, van't Veer Laura J, Rookus Matti A
Abstract excerpt
Insulin-like growth factor-I (IGF-I) is an important growth factor associated with increased risk of premenopausal breast cancer. We conducted a randomized, placebo-controlled, double-blind, crossover trial to evaluate whether tomato-derived lycopene supplementation (30 mg/day for 2 mo) decreases serum levels of total IGF-I in premenopausal women with 1) a history of breast cancer (n=24) or 2) a high familial...
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