Article

TRIM29 is Critical for Bladder Cancer Progression and Modulates the Tumor-Immune Niche

2026-05-20

Abstract excerpt

<title>Abstract</title> <p>TRIM29 (Tripartite Motif-Containing Protein 29), also known as ATDC (Ataxia-Telangiectasia Group D-Complementing Protein), is an E3 ubiquitin ligase frequently upregulated in muscle-invasive bladder cancer (MIBC). We have previously shown that TRIM29 overexpression in a genetically engineered mouse model (GEMM) is sufficient to drive development of MIBC. We have also shown that TRIM29 i...

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Literature Corpus work: 4d587692-b8a0-5c9b-92df-268c36b20e55
DOI: 10.21203/rs.3.rs-9214925/v1

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