Article

Bioengineering an Ultra-Stable and Cost-Effective FGF2 (NGF2) with Extended Circulatory Half-Life for Next-Generation Therapeutics

2026-07-10

Abstract excerpt

<title>Abstract</title> <p> Human fibroblast growth factor 2 (FGF2) is one of the potent signaling proteins for various therapeutic applications, especially in cell regeneration. However, the clinical translation of FGF2 has been constrained by two major hurdles, which are inherent instability in solution (< 1 h stability) and an unacceptably short circulation half-life (< 1 day). Compensatory strategies such as...

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Literature Corpus work: 4d44ca0e-8172-58f5-8bac-bb6d1dd02c84
DOI: 10.21203/rs.3.rs-10239074/v1

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