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Genetically predicted telomere length and its relationship with neurodegenerative diseases and life expectancy

1 Jan 2022

Abstract excerpt

Telomere length (TL) is a biomarker of biological aging. Shorter telomeres have been associated with mortality and increased rates of age-related diseases. However, observational studies are unable to conclude whether TL is causally associated with those outcomes. Mendelian randomization (MR) was developed for assessing causality using genetic variants in epidemiological research. The objective of this study was...

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Share to Epigenetics and DNA Methylation
Share to Genetics, Aging, and Longevity in Model Organisms
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36051868
DOI: 10.1016/j.csbj.2022.08.006

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