Article
High affinity hemoglobin and Parkinson's disease.
Medical hypotheses - 1 Dec 2014
Graham Jeffrey, Hobson Douglas, Ponnampalam Arjuna
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra (SN) region of the midbrain. Oxidative damage in this region has been shown to play an important role in the pathogenesis of this disease. Human neurons have been discovered to contain hemoglobin, with an increased concentration seen in the neurons of the SN. High affinity hemoglobin...
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