Article

The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic.

2022-03-16

Abstract excerpt

<title>Abstract</title> <p><italic>Clostridioides difficile</italic> infection (CDI) causes substantial morbidity and mortality worldwide with limited antibiotic treatment options. Ridinilazole is a precision bisbenzimidazole antibiotic being developed to treat CDI and reduce unacceptably high rates of infection recurrence in patients. Although in Phase 3 clinical development, the precise mechanism of action by w...

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Literature Corpus work: 4d08d71d-33a9-524d-98f9-883a1d4a77db
DOI: 10.21203/rs.3.rs-1396940/v1

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