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Article

PLCL1 suppresses tumor progression by regulating AMPK/mTOR-mediated autophagy in renal cell carcinoma

2022-04-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Autophagy has been increasingly recognized as a critical regulatory mechanism in the maintenance of cellular homeostasis. A previous study showed that phospholipase C-like protein 1 (PLCL1) is associated with the lipid metabolism of clear cell renal cell carcinoma (ccRCC). However, it is unclear whether PLCL1 regulates autophagy, thereby influencing the progress...

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Literature Corpus work
88534e61-24db-54c8-a6ee-95419762a7ff
DOI
10.21203/rs.3.rs-1501645/v1
Open publication

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