Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer Cells

5 Aug 2013

Abstract excerpt

Tissue inhibitor of metalloproteinase 1 (TIMP-1) is a protein with a potential biological role in drug resistance. To elucidate the unknown molecular mechanisms underlying the association between high TIMP-1 levels and increased chemotherapy resistance, we employed SILAC-based quantitative mass spectrometry to analyze global proteome and phosphoproteome differences of MCF-7 breast cancer cells expressing high or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Protease and Inhibitor Mechanisms
Share to Signaling Pathways in Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23909892
DOI: 10.1021/pr400457u

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TIMP-1 Increases Expression and Phosphorylation of Proteins Associated with Drug Resistance in Breast Cancer CellsPMID 23909892Read ↗

Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancerSemantic proximity Read ↗

Biological and Clinical Significance of TIMPs Expression in Breast Cancer: a Bioinformatic AnalysisSemantic proximity Read ↗

Unraveling TIMP1: a multifaceted biomarker in colorectal cancerSemantic proximity Read ↗

A Comprehensive Bioinformatics Analysis of TIMP2 in Multiple MalignanciesSemantic proximity Read ↗

Multi-omics Analysis and Functional Characterization of the TIMP1 in Colorectal CancerSemantic proximity Read ↗

TIMP‐1 expression in human colorectal cancer is associated with TGF‐B1, LOXL2, INHBA1, TNF‐AIP6 and TIMP‐2 transcript profilesSemantic proximity Read ↗

Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancerSemantic proximity Read ↗

Whole Organism Profiling of the Timp Gene FamilySemantic proximity Read ↗

An integrative analysis reveals the prognostic and immunological role of TIMP gene family in pan-cancerSemantic proximity Read ↗

The TIMP protein family: diverse roles in pathophysiologySemantic proximity Read ↗

Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype.Semantic proximity Read ↗

Identification of a Putative Protein Profile Associated with Tamoxifen Therapy Resistance in Breast CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.