Article

Hypermethylation of RAD9A intron 2 in childhood cancer patients, leukemia and tumor cell lines suggest a role for oncogenic transformation

2020-08-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Most childhood cancers occur sporadically and cannot be explained by an inherited mutation or an unhealthy lifestyle. This suggests other predisposition defects that may support the oncogenic transformation of cells, e.g. via impaired DNA-repair. Our study consequently aims to investigate the impact of increased methylation of intron 2 of RAD9A in cancer patient...

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Literature Corpus work: 4bf38cf3-4d14-5624-84e3-f0a82f7627f2
DOI: 10.21203/rs.3.rs-55470/v1

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