Article
Molecular karyotyping and gene expression analysis in childhood cancer patients.
Journal of molecular medicine (Berlin, Germany) - 1 Aug 2020
Danuta Galetzka, Tobias Müller, Marcus Dittrich, Miriam Endres, Nergiz Kartal, Olesja Sinizyn, Steffen Rapp, Tanja Zeller, Christian Müller, Thomas Hankeln, Peter Scholz-Kreisel, Heather Chorzempa, Johanna Mirsch, Alicia Poplawski, Heidi Rossmann, Claudia Spix, Thomas Haaf, Dirk Prawitt, Manuela Marron, Heinz Schmidberger
Abstract excerpt
The genetic etiology of sporadic childhood cancer cases remains unclear. We recruited a cohort of 20 patients who survived a childhood malignancy and then developed a second primary cancer (2N), and 20 carefully matched patients who survived a childhood cancer without developing a second malignancy (1N). Twenty matched cancer-free (0N) and additional 1000 (0N) GHS participants served as controls. Aiming to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.