Article

Circulating miR-10b-5p drives Kawasaki vasculitis through endothelial reprogramming and nominates CXCL8 as an early diagnostic biomarker

2026-03-16

Abstract excerpt

<h4>Background</h4> Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology and the leading cause of acquired heart disease in children. Coronary artery aneurysm formation represents its most serious complication, yet no specific biomarker exists for early diagnosis at emergency department (ED) presentation. We sought to define the molecular mechanisms driving KD vasculitis and to identify a cli...

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Literature Corpus work: aa62121b-7825-51bc-876f-0252b8057230
DOI: 10.64898/2026.03.12.711476

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