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OmniPert: A Deep Learning Foundation Model for Predicting Responses to Genetic and Chemical Perturbations in Single Cancer Cells

2025-07-05

Abstract excerpt

In cancer, intra- and inter-patient heterogeneity presents a significant challenge for therapeutic management, as patients with apparently similar profiles often exhibit divergent responses to the same therapies. This heterogeneity is primarily attributed to genetic and molecular variations among individuals and their tumors. Understanding the impact of these differences on treatment outcomes is widely believed to...

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Literature Corpus work
a792e7a1-bb07-5072-a1af-9ab915943de7
DOI
10.1101/2025.07.02.662744
Open publication

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OmniPert: A Deep Learning Foundation Model for Predicting Responses to Genetic and Chemical Perturbations in Single Cancer CellsDOI 10.1101/2025.07.02.662744
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