Article

PertEval-scFM: Benchmarking Single-Cell Foundation Models for Perturbation Effect Prediction

2024-10-03

Abstract excerpt

In silico modeling of transcriptional responses to perturbations is crucial for advancing our understanding of cellular processes and disease mechanisms. We present PertEval-scFM, a standardized framework designed to evaluate models for perturbation effect prediction. We apply PertEval-scFM to benchmark zero-shot single-cell foundation model (scFM) embeddings against base-line models to assess whether these contex...

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Literature Corpus work: cf99b272-aa0b-5717-a5b9-1099bccf0aa9
DOI: 10.1101/2024.10.02.616248

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