Article

Pharmacodynamics and biodistribution of radiolabeled Platinum-195m (Cisspect) in head and neck squamous cell carcinoma

2023-10-14

Abstract excerpt

<title>Abstract</title> <p>Background Cisplatin- based chemoradiotherapy is a crucial pillar in the treatment of HNSCC. The use of cisplatin comes with a high burden as 35% of patients cannot sustain the planned dose. Unfortunately, there are no clinically applicable biomarkers to predict response. Based on the association of response with the number of DNA adducts and the involved molecular pathway to resolve c...

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Literature Corpus work: 4b8656e8-ea7a-5f6b-8341-b37c60db4c10
DOI: 10.21203/rs.3.rs-3407439/v1

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