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Article

KiSS1 mediates platinum sensitivity and metastasis suppression in head and neck squamous cell carcinoma.

Oncogene - 14 Jul 2011

Jiffar T, Yilmaz T, Lee J, Hanna E, El-Naggar A, Yu D, Myers J N, Kupferman M E

Abstract excerpt

Although surgery and radiotherapy have been the standard treatment modalities for head and neck squamous cell carcinoma (HNSCC), the integration of cisplatin (CDDP)-based therapy has led to improvements in local and regional control of disease for patients. However, many trials show that only 10-20% of patients benefit from this treatment intensification, which can result in profound treatment-associated...

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Share to Carcinoma, Squamous Cell
Share to Cisplatin
Share to Glutathione Transferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

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Share to Neoplasm Metastasis

Share to Suppression, Genetic

Share to Tumor Suppressor Proteins

Source

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Identifiers

PMID: 21383688
DOI: 10.1038/onc.2011.39
PMCID: PMC3136629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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