Article

Strategies to Overcome Intrinsic and Acquired Resistance to Chemoradiotherapy in Head and Neck Cancer

2024-12-17

Abstract excerpt

Definitive chemoradiotherapy (CRT) is a cornerstone of treatment for locoregionally advanced head and neck cancer (HNC). Research is ongoing on how to improve the tumor response to treatment and limit normal tissue toxicity. A major limitation in that regard is the growing number of intrinsic or acquired treatment resistance in advanced cases. In this review, we will discuss how overexpression of efflux pumps, per...

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Literature Corpus work: 4bcd45ae-9938-5e22-b37e-cffd57800f1b
DOI: 10.20944/preprints202412.1383.v1

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