Article

Expression variation analysis for tumor heterogeneity in single-cell RNA-sequencing data

2018-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Tumor heterogeneity provides a complex challenge to cancer treatment and is a critical component of therapeutic response, disease recurrence, and patient survival. Single-cell RNA-sequencing (scRNA-seq) technologies reveal the prevalence of intra-and inter-tumor heterogeneity. Computational techniques are essential to quantify the differences in variation of these profiles between distinct cell...

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Literature Corpus work: 4b861be5-89f1-5211-9316-48ab26c8a1ee
DOI: 10.1101/479287

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