Article

3D-bioprinted patient-specific organotypic bone model mimicking mineralization dysregulation in <i>FKBP10</i> -related osteogenesis imperfecta

2024-05-21

Abstract excerpt

Osteogenesis imperfecta (OI) is a heterogeneous group of rare genetic diseases characterized by increased bone fragility and deformities. The pathomechanisms of OI are poorly understood, hindering the development of disease-specific therapy. Addressing the limited understanding of OI and the lack of targeted treatments remains a challenge, given its varied symptoms and large clinical spectrum. Animal models have g...

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Literature Corpus work: 4b0eee1b-01bd-5e40-8168-a59cc9e3fc5a
DOI: 10.1101/2024.05.20.594917

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