Article
The intrinsically disordered N-terminus of the voltage-dependent anion channel.
PLoS computational biology - 1 Feb 2021
Preto Jordane, Krimm Isabelle
Abstract excerpt
The voltage-dependent anion channel (VDAC) is a critical β-barrel membrane protein of the mitochondrial outer membrane, which regulates the transport of ions and ATP between mitochondria and the cytoplasm. In addition, VDAC plays a central role in the control of apoptosis and is therefore of great interest in both cancer and neurodegenerative diseases. Although not fully understood, it is presumed that the gating...
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