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Phage production is blocked in the adherent-invasive Escherichia coli LF82 upon macrophage infection

2 Feb 2023

Abstract excerpt

Adherent-invasive Escherichia coli (AIEC) strains are frequently recovered from stools of patients with dysbiotic microbiota. They have remarkable properties of adherence to the intestinal epithelium, and survive better than other E. coli in macrophages. The best studied of these AIEC is probably strain LF82, which was isolated from a Crohn's disease patient. This strain contains five complete prophages, which...

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PMID: 36730457
DOI: 10.1371/journal.ppat.1011127

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