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A rapid, multiplex digital PCR assay for <i>EGFR</i> , <i>KRAS</i> , <i>BRAF</i> , <i>ERBB2</i> variants and <i>ALK</i> , <i>RET</i> , <i>ROS1</i> , <i>NTRK1</i> gene fusions in non-small cell lung cancer

2023-03-12

Abstract excerpt

Digital PCR (dPCR) is emerging as an ideal platform for the detection and tracking of genomic variants in cancer due to its high sensitivity and simple workflow. The growing number of clinically-actionable cancer biomarkers creates a need for fast, accessible methods that allow for dense information content and high accuracy. Here, we describe a proof-of-concept amplitude modulation based multiplex dPCR assay capa...

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Literature Corpus work
4a71c09b-a6c6-50b6-9f3f-3388004bbe21
DOI
10.1101/2023.03.09.531949
Open publication

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A rapid, multiplex digital PCR assay for <i>EGFR</i> , <i>KRAS</i> , <i>BRAF</i> , <i>ERBB2</i> variants and <i>ALK</i> , <i>RET</i> , <i>ROS1</i> , <i>NTRK1</i> gene fusions in non-small cell lung cancerDOI 10.1101/2023.03.09.531949
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