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All-In-One OsciDrop Digital PCR System for Automated and Highly Multiplexed Molecular Diagnostics.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Jun 2024

Li Caiming, Kang Nan, Ye Shun, Huang Weihang, Wang Xia, Wang Cheng, Li Yuchen, Liu Yan-Fei, Lan Ying, Ma Liang, Zhao Yuhang, Han Yong, Fu Jun, Shen Danhua, Dong Lianhua, Du Wenbin

Abstract excerpt

Digital PCR (dPCR) holds immense potential for precisely detecting nucleic acid markers essential for personalized medicine. However, its broader application is hindered by high consumable costs, complex procedures, and restricted multiplexing capabilities. To address these challenges, an all-in-one dPCR system is introduced that eliminates the need for microfabricated chips, offering fully automated operations...

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PMID: 38516754
DOI: 10.1002/advs.202309557
PMCID: PMC11151056

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EGFR

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