Article

Nuclear Respiratory Factor 1 (NRF-1) Controls the Activity Dependent Transcription of the GABA-A Receptor Beta 1 Subunit Gene in Neurons

2018-05-14

Abstract excerpt

<h4>ABSTRACT</h4> While the exact role of β1 subunit-containing GABA-A receptors (GABARs) in brain function is not well understood, altered expression of the β1 subunit gene ( GABRB1 ) is associated with neurological and neuropsychiatric disorders. In particular, down-regulation of β1 subunit levels is observed in brains of patients with epilepsy, autism, bipolar disorder, and schizophrenia. A pathophysiological...

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Literature Corpus work: 4a71b6af-97b7-59ce-a7a5-d8eead7aceef
DOI: 10.1101/321257

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