Article
Four Structurally Distinct, Non-DNA-Binding Subunits of Human Nuclear Respiratory Factor 2 Share a Conserved Transcriptional Activation Domain
1 Jan 1995
Abstract excerpt
Nuclear respiratory factor 2 (NRF-2) was previously purified to near homogeneity from HeLa cells on the basis of its ability to bind tandem recognition sites in the rat cytochrome oxidase subunit IV (RCO4) promoter. It consisted of five subunits, alpha, beta 1, beta 2, gamma 1, and gamma 2. Sequencing of tryptic peptides from alpha and from mixtures of the two beta or two gamma subunits revealed sequence...
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